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Michele Senni Selected Research

sacubitril and valsartan sodium hydrate drug combination

4/2022[Position paper of the Italian Society of Cardiology: The renin-angiotensin-aldosterone system blockade in heart failure patients - Part II: Mechanistic effects of sacubitril/valsartan, placement in current guidelines and use in clinical practice].
3/2022[Position paper of the Italian Society of Cardiology: The renin-angiotensin-aldosterone system (RAAS) blockade in heart failure patients - Part I: From RAAS identification to clinical trials].
1/2022Renin-angiotensin-aldosterone system inhibition in patients affected by heart failure: efficacy, mechanistic effects and practical use of sacubitril/valsartan. Position Paper of the Italian Society of Cardiology.
1/2022Angiotensin-neprilysin inhibition and renal outcomes across the spectrum of ejection fraction in heart failure.
1/2022Impact of Sacubitril/Valsartan Versus Ramipril on Total Heart Failure Events in the PARADISE-MI Trial.
1/2022Efficacy and safety of vericiguat in patients with heart failure with reduced ejection fraction treated with sacubitril/valsartan: insights from the VICTORIA trial.
11/2021Angiotensin Receptor-Neprilysin Inhibition in Acute Myocardial Infarction.
10/2021Sacubitril/valsartan in real-life European patients with heart failure and reduced ejection fraction: a systematic review and meta-analysis.
3/2021Rationale for and Practical Use of Sacubitril/Valsartan in the Patient's Journey with Heart Failure and Reduced Ejection Fraction.
1/2021Real-world effectiveness and safety of sacubitril/valsartan in heart failure: A systematic review.
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Michele Senni Research Topics

Disease

108Heart Failure
04/2022 - 11/2002
16COVID-19
12/2022 - 03/2020
10Myocardial Infarction
11/2021 - 09/2014
9Hypotension (Low Blood Pressure)
01/2022 - 05/2005
9Atrial Fibrillation
01/2022 - 11/2013
8Mitral Valve Insufficiency (Mitral Regurgitation)
01/2022 - 10/2009
7Hemorrhage
10/2021 - 02/2015
7Left Ventricular Dysfunction
01/2020 - 11/2002
6Cardiomyopathies (Cardiomyopathy)
01/2022 - 10/2009
5Coronary Artery Disease (Coronary Atherosclerosis)
01/2021 - 05/2012
5Heart Diseases (Heart Disease)
11/2020 - 01/2018
4Chronic Obstructive Pulmonary Disease (COPD)
12/2021 - 12/2002
4ST Elevation Myocardial Infarction
01/2021 - 01/2017
4Cardiovascular Diseases (Cardiovascular Disease)
11/2018 - 02/2015
3Chronic Renal Insufficiency
01/2022 - 01/2018
3Stroke (Strokes)
10/2021 - 02/2015
3Disease Progression
07/2021 - 01/2015
3Acute Coronary Syndrome
01/2021 - 02/2020
3Anemia
01/2021 - 05/2011
3Angioedema
10/2019 - 01/2017
3Hypertrophy
01/2019 - 12/2014
2Chronic Kidney Failure (Chronic Renal Failure)
01/2022 - 01/2020
2Hypertension (High Blood Pressure)
10/2021 - 01/2021
2Pulmonary Embolism
03/2021 - 11/2020
2Hyperkalemia
10/2019 - 03/2015
2Fibrosis (Cirrhosis)
01/2019 - 10/2018
2Systolic Heart Failure
01/2018 - 09/2014
2Thrombosis (Thrombus)
04/2017 - 05/2016
2Ventricular Dysfunction
09/2014 - 11/2013
1Frailty
11/2021
1Urinary Tract Infections (Urinary Tract Infection)
10/2021
1Inflammation (Inflammations)
07/2021
1Renal Insufficiency (Renal Failure)
03/2021
1Liver Diseases (Liver Disease)
01/2021
1Peripheral Arterial Disease
01/2021
1Neoplasms (Cancer)
01/2021

Drug/Important Bio-Agent (IBA)

35sacubitril and valsartan sodium hydrate drug combinationIBA
04/2022 - 01/2015
18Neprilysin (Neutral Endopeptidase)IBA
03/2022 - 01/2015
13Pharmaceutical PreparationsIBA
04/2022 - 03/2015
13Angiotensin Receptors (Angiotensin II Receptor)IBA
03/2022 - 01/2015
10Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
11/2021 - 01/2015
9TroponinIBA
12/2022 - 01/2017
9pro-brain natriuretic peptide (1-76)IBA
04/2022 - 05/2014
9Natriuretic PeptidesIBA
03/2022 - 10/2013
9EnalaprilFDA LinkGeneric
03/2022 - 01/2015
9Biomarkers (Surrogate Marker)IBA
01/2022 - 09/2014
8Brain Natriuretic Peptide (Natrecor)FDA Link
06/2021 - 05/2014
7AngiotensinsIBA
03/2022 - 01/2015
7Valsartan (Vals)FDA Link
01/2022 - 01/2018
6paragonIBA
01/2022 - 01/2018
5empagliflozinIBA
04/2022 - 10/2020
5vericiguatIBA
01/2022 - 10/2020
5Angiotensin Receptor AntagonistsIBA
12/2021 - 01/2017
5AnticoagulantsIBA
10/2021 - 08/2017
5Mineralocorticoid Receptor AntagonistsIBA
10/2021 - 09/2014
4CreatinineIBA
12/2021 - 11/2012
4Uric Acid (Urate)IBA
06/2021 - 12/2014
4DiureticsIBA
01/2021 - 05/2005
4Oxygen (Dioxygen)IBA
01/2021 - 01/2019
3sacubitrilIBA
11/2021 - 10/2019
3TolvaptanFDA Link
02/2016 - 09/2014
2ReninIBA
03/2022 - 01/2021
2Ramipril (Altace)FDA LinkGeneric
01/2022 - 11/2021
2Sodium-Glucose Transport ProteinsIBA
10/2021 - 10/2020
2CalciumIBA
09/2021 - 01/2021
2Biological ProductsIBA
07/2021 - 01/2018
2AlbuminsIBA
06/2021 - 05/2021
2ChloridesIBA
06/2021 - 05/2021
2BilirubinIBA
06/2021 - 05/2021
2Hormones (Hormone)IBA
06/2021 - 05/2021
2ElectrolytesIBA
03/2021 - 09/2014
2Hemoglobins (Hemoglobin)IBA
01/2021 - 05/2011
2Carbon DioxideIBA
01/2021 - 01/2019
2fulacimstatIBA
01/2020 - 10/2019
2Chymases (Chymase)IBA
01/2020 - 10/2019
2neladenoson bialanateIBA
11/2019 - 01/2017
2Adenosine A1 ReceptorIBA
11/2019 - 01/2017
2Indicators and Reagents (Reagents)IBA
01/2018 - 09/2014
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
01/2017 - 01/2015
2omega-Chloroacetophenone (Mace)IBA
11/2015 - 02/2015
2Vasopressins (Vasopressin)IBA
12/2014 - 09/2014
1AldosteroneIBA
03/2022
1BAY 58-2667IBA
01/2022
1SteroidsIBA
10/2021
1Myosins (Myosin)IBA
10/2021
1GlucocorticoidsIBA
07/2021
1fibrin fragment D (D-dimer)IBA
07/2021

Therapy/Procedure

41Therapeutics
01/2022 - 10/2002
7Patient Readmission
10/2020 - 11/2002
5Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
01/2022 - 11/2012
5Cardiac Resynchronization Therapy
01/2019 - 10/2009
4Heart Transplantation (Grafting, Heart)
11/2021 - 10/2009
4Percutaneous Coronary Intervention
01/2021 - 11/2015
3Coronary Artery Bypass (Coronary Artery Bypass Surgery)
09/2018 - 05/2012
3Stents
04/2017 - 02/2015
2Critical Care (Surgical Intensive Care)
03/2020 - 01/2015
2Bioprosthesis
01/2018 - 12/2002
2Heart-Assist Devices
10/2015 - 10/2009
2Mitral Valve Annuloplasty
06/2015 - 08/2014
1Hand Hygiene
11/2021